NEWTOWN — A 12:20 p.m. collision closed a stretch of Route 25 for more than four hours Tuesday, according to police.

The state Department of Transportation reported Route 25 — South Main Street — was closed at Pecks Lane as crews investigated and worked to clear the site of a two-vehicle collision.

At 4:50 p.m., police said the roadway had reopened to motorists.

There was no immediate word on possible injuries.

This is a developing story. Check back for updates.